Mfg Part Number
Ab04028-10.0
Vector Labs Ab04028-10.0 Anti-VEGFR-3 [ABDD073], Human IgG1, kappa (100 μg)
Quick Overview
The original antibody was generated by immunizing BALB/C mice with VEGFR-3/Ig recombinant protein.
$570.70
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| Product Class: | Purified |
|---|---|
| Clone ID: | ABDD073 |
| Synonyms: | FLT-4; Vascular endothelial growth factor receptor 3; EC:2.7.10.1; Fms-like tyrosine kinase 4; Tyrosine-protein kinase receptor FLT4 |
| Amount: | 100 μg |
| Application Codes Clone: | ELISA; IHC; FC |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | IgG2a |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Chimeric Use Statement: | This chimeric human antibody was made using the variable domain sequences of the original Mouse IgG2a format, for improved compatibility with existing reagents, assays and techniques. |
| Specificity Statement: | The antibody is specific for VEGFR-3. |
| Application Notes: | The antibody showed neutralizing activity by ELISA analysis. The antibody detected VEGFR-3 from HEL cell lysates by western blot analysis. The antibody could recognize VEGRF-3 on fetal heart, fetal kidney and fetal lung tissue by immunohistochemistry. The binding activity of the antibody to VEGFR-3 expressed on the surface of HEL cells was confirmed by FACS flow cytometry. In vitro experiments showed the antibody could block the interaction between VEGFR-3 and VEGF-D. The antibody could inhibit HEL cell proliferation. The antibody could inhibit the generation of chicken embryo allantoic membrane blood vessels induced by recombinant GST-VEGF-D (CN1800373A). |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |