Mfg Part Number
Ab04104-2.0
Vector Labs Ab04104-2.0 Anti-Nkp46 [29A1.4], Mouse IgG2a, kappa (100 μg)
Quick Overview
The original antibody was generated by immunizing rats with mouse NKp46-Fc recombinant protein.
$570.70
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| Product Class: | Purified |
|---|---|
| Clone ID: | 29A1.4 |
| Synonyms: | CD335; NK-p46; NKp46; mNKp46; mAR-1; Activating receptor 1; Lymphocyte antigen 94; Natural killer cell p46-related protein; Natural cytotoxicity triggering receptor 1 |
| Amount: | 100 μg |
| Application Codes Clone: | FC; Activation |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | IgG2a |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Chimeric Use Statement: | This chimeric mouse antibody was made using the variable domain sequences of the original Rat IgG2a format, for improved compatibility with existing reagents, assays and techniques. |
| Specificity Statement: | This antibody is specific for mouse NKp46-Fc. |
| Application Notes: | The original format of this antibody was used in an FC analysis to detect NKp46 expression on NK cells and to activate NK in an NK cell stimulation assay (Walzer et al., 2007; PMID: 17360655). This antibody was used as a component of bispecific NKCEs (Natural Killer Cell Engagers) to redirect the cytotoxic activity of NK cells towards human CD20-expressing tumor cells in a transplantable xenogeneic in vivo solid tumor model (Gauthier et al., 2019; PMID: 31155232). |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |