Mfg Part Number
Ab04124-10.0
Vector Labs Ab04124-10.0 Anti-VEGFR2 [B1A1], Human IgG1, lambda (100 μg)
Quick Overview
The original antibody was isolated by panning a phage display library against VEGFR2.
$570.70
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| Product Class: | Purified |
|---|---|
| Clone ID: | B1A1 |
| Synonyms: | flk-1;FLK-1; KDR; Fetal liver kinase 1; Kinase insert domain receptor; Protein-tyrosine kinase receptor; EC:2.7.10.1; Vascular endothelial growth factor receptor 2; Vascular endothelial growth factor receptor |
| Amount: | 100 μg |
| Application Codes Clone: | SPR |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | IgG1 |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Specificity Statement: | The antibody is specific for VEGFR2. |
| Application Notes: | The bispecific antibody (A1-A8)-LALA associated with either VEGFR2 or PDLl fast and stayed on either VEGFR2 or PDLl long (KD values of BsAb (A1-A8) were about 200 pM and 3.2 pM for the hVEGFR2 and hPDLl). A cytokine secretion assay was carried out with the bispecific antibody and B1A1. The results indicate that in the present of BsAb (A1-A8)-LALA, the secretion of cytokine IL2 and INFy in PBMC when stimulated by SEB was higher than the control antibody B1A1, demonstrating that BsAb (A1-A8)-LALA retains the potency of its parental antibody B1A1 (against VEGFR2) and dsD7A8-LALA (against PDL1) (EP3411068A4). |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |