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Mfg Part Number

Ab04130-23.0

Vector Labs Ab04130-23.0 Anti-Envelope glycoprotein H and L [94], Rabbit IgG, kappa (100 μg)

VECTOR LABS

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Quick Overview

The original antibody was isolated from a combinatorial library of human antibodies (AIMS4) using a phage-display system by panning the library against purified varicella-zoster virus (VZV) gH:gL complex.

$570.70

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Description

Product Class: Purified
Clone ID: 94
Synonyms: gHgL; gH; gL; envelope glycoprotein H; envelope glycoprotein L; Varicella zoster virus; VZV; human herpesvirus 3; HHV-3; HHV3; Human alpha herpesvirus 3; Chickenpox; VZ94; IgG-94
Amount: 100 μg
Application Codes Clone: ELISA; neutralize; IP
Shipping Temperature: Wet Ice
Buffer Composition: PBS with 0.02% Proclin 300.
Original Format: IgG1
Storage Temperature: Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C.
Chimeric Use Statement: This chimeric rabbit antibody was made using the variable domain sequences of the original Human IgG1 format, for improved compatibility with existing reagents, assays and techniques.
Specificity Statement: This antibody targets the domain IV region of envelope glycoprotein B of the Varicella zoster virus (VZV) also known as the human herpesvirus 3 (HHV-3, HHV3) or Human alpha herpesvirus 3. This DNA virus from the herpes virus group can infect humans causing chickenpox in children and shingles (herpes zoster) in adults. Varicella is characterized by a maculopapular, vesicular rash that can be pruritic and evolves into dried crusts (scabs) over a 3- to 7-day period. Chicken pox is considered contagious beginning 1-2 days before rash onset until all lesions have crusted (scabbed).
Application Notes: This antibody reacted with gH and gL in an ELISA. This antibody was also capable of reacting with gH:gL complex and VZV-infected cells. This antibody was used for the immunoperoxidase staining of VZV-infected human embryonic lung (HEL) cells. This antibody neutralized wild strains without showing strain specificity. This antibody was also reported to prevent the spreading of virus infection. This antibody was also capable of immunoprecipitating gH and gL glycoproteins of VZV (PMID: 17457901).

Product Class:	Purified
Clone ID:	94
Synonyms:	gHgL; gH; gL; envelope glycoprotein H; envelope glycoprotein L; Varicella zoster virus; VZV; human herpesvirus 3; HHV-3; HHV3; Human alpha herpesvirus 3; Chickenpox; VZ94; IgG-94
Amount:	100 μg
Application Codes Clone:	ELISA; neutralize; IP
Shipping Temperature:	Wet Ice
Buffer Composition:	PBS with 0.02% Proclin 300.
Original Format:	IgG1
Storage Temperature:	Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C.
Chimeric Use Statement:	This chimeric rabbit antibody was made using the variable domain sequences of the original Human IgG1 format, for improved compatibility with existing reagents, assays and techniques.
Specificity Statement:	This antibody targets the domain IV region of envelope glycoprotein B of the Varicella zoster virus (VZV) also known as the human herpesvirus 3 (HHV-3, HHV3) or Human alpha herpesvirus 3. This DNA virus from the herpes virus group can infect humans causing chickenpox in children and shingles (herpes zoster) in adults. Varicella is characterized by a maculopapular, vesicular rash that can be pruritic and evolves into dried crusts (scabs) over a 3- to 7-day period. Chicken pox is considered contagious beginning 1-2 days before rash onset until all lesions have crusted (scabbed).
Application Notes:	This antibody reacted with gH and gL in an ELISA. This antibody was also capable of reacting with gH:gL complex and VZV-infected cells. This antibody was used for the immunoperoxidase staining of VZV-infected human embryonic lung (HEL) cells. This antibody neutralized wild strains without showing strain specificity. This antibody was also reported to prevent the spreading of virus infection. This antibody was also capable of immunoprecipitating gH and gL glycoproteins of VZV (PMID: 17457901).

Specifications

More Information
Brand	Vector Labs
UNSPSC	12161500

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