Mfg Part Number
Ab04131-10.0
Vector Labs Ab04131-10.0 Anti-Envelope glycoprotein H and L [rec-RC-IgG], Human IgG1, kappa (100 μg)
Quick Overview
The original antibody was isolated from circulating blood plasmablast of a 59-year-old VZV-seropositive man recently immunized with zoster vaccine Zostavax.
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| Product Class: | Purified |
|---|---|
| Clone ID: | rec-RC-IgG |
| Synonyms: | gHgL; gH; gL; envelope glycoprotein H; envelope glycoprotein L; Varicella zoster virus; VZV; human herpesvirus 3; HHV-3; HHV3; Human alpha herpesvirus 3; Chickenpox; IgG-RC |
| Amount: | 100 μg |
| Application Codes Clone: | IHC; IP; neutralize |
| Shipping Temperature: | Wet Ice |
| Origin Pub PMID: | 23077312 |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | IgG1 |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Specificity Statement: | This antibody targets the domain IV region of envelope glycoprotein B of the Varicella zoster virus (VZV) also known as the human herpesvirus 3 (HHV-3, HHV3) or Human alpha herpesvirus 3. This DNA virus from the herpes virus group can infect humans causing chickenpox in children and shingles (herpes zoster) in adults. Varicella is characterized by a maculopapular, vesicular rash that can be pruritic and evolves into dried crusts (scabs) over a 3- to 7-day period. Chicken pox is considered contagious beginning 1-2 days before rash onset until all lesions have crusted (scabbed). |
| Application Notes: | This antibody was used for the immunohistochemical staining of fixed and unfixed VZV-infected and control human lung fibroblast cells. This antibody was also reported to neutralize VZV infection in a plaque reduction assay. The concentration of IgG that produced 50% plaque reduction was 0.6 μg/ml. This antibody was also used for the immunoprecipitation of VZV-infected cells (PMID: 23077312). |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |