Mfg Part Number
Ab04142-23.0
Vector Labs Ab04142-23.0 Anti-RANK-L [RL], Rabbit IgG, lambda (100 μg)
Quick Overview
The original antibody was generated by panning a Fab library against RANKL.
$570.70
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| Product Class: | Purified |
|---|---|
| Clone ID: | RL |
| Synonyms: | CD254; TRANCE; RANKL; ODF; OPGL; Tumor necrosis factor ligand superfamily member 11; Osteoclast differentiation factor; Osteoprotegerin ligand; Receptor activator of nuclear factor kappa-B ligand; TNF-related activation-induced cytokine |
| Amount: | 100 μg |
| Application Codes Clone: | ELISA; blocking |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | Fab |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Chimeric Use Statement: | This chimeric rabbit antibody was made using the variable domain sequences of the original Human Fab format, for improved compatibility with existing reagents, assays and techniques. |
| Specificity Statement: | The antibody is specific for human-RANK-L. RANKL is a tumor necrosis factor (TNF)-related protein that binds to, and activates, the TNF receptor (TNFR)-related protein Receptor Activator of NF-kB (RANK). RANKL acts as the key cytokine that regulates osteoclast differentiation and activation during normal bone remodeling and during disease. |
| Application Notes: | The origina antibody was capable of blocking the interactions between RANKL and its receptor RANK. The original antibody could potentially be used in an ELISA analysis (WO2015030701A1) |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |