Mfg Part Number
Ab04151-23.0
Vector Labs Ab04151-23.0 Anti-CD147 [059-053], Rabbit IgG, lambda (100 μg)
Quick Overview
The original antibody was isolated by panning a phage display library against CD147.
$570.70
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| Product Class: | Purified |
|---|---|
| Clone ID: | 059-053 |
| Synonyms: | 5F7; TCSF; Basigin; Collagenase stimulatory factor; Collagenase stimulatory factor; Extracellular matrix metalloproteinase inducer; EMMPRIN; Hepatoma-associated antigen; HAb18G; Leukocyte activation antigen M6; OK blood group antigen; Tumor cell-derived collagenase stimulatory factor |
| Amount: | 100 μg |
| Application Codes Clone: | ADCC |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | scFv |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Chimeric Use Statement: | This full-length, chimeric rabbit antibody was made using the variable domain sequences of the original Human scFv format, for improved compatibility with existing reagents, assays and techniques. |
| Specificity Statement: | The antibody is specific for CD147. CD147 acts as a retinal cell surface receptor for NXNL1 and plays an important role in NXNL1-mediated survival of retinal cone photoreceptors. Further, in association with glucose transporter SLC16A1/GLUT1 and NXNL1, promotes retinal cone survival by enhancing aerobic glycolysis and accelerating the entry of glucose into photoreceptors. |
| Application Notes: | The IgG1 format of the antibody specifically bound to the cancer cells expressing CD147 (CCF-RC1, ACHN) and expresses the ADCC activity (US9388249B2). |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |