Mfg Part Number
Ab04152-2.3
Vector Labs Ab04152-2.3 Anti-IL-25 [ABM109.2], Mouse IgG2a, Fc Silent™, kappa (100 μg)
Quick Overview
The antibody is the humanized version of the parental ABM109.
$570.70
Order will ship within 1-3 business days
| Product Class: | Purified |
|---|---|
| Clone ID: | ABM109.2 |
| Heavy Chain Modification: | Fc Silent™ |
| Synonyms: | Interleukin-25; Interleukin-17E; IL-17E |
| Amount: | 100 μg |
| Application Codes Clone: | SPR; Neutralizing |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | IgG1 |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Chimeric Use Statement: | This chimeric mouse antibody was made using the variable domain sequences of the original Human IgG1 format, for improved compatibility with existing reagents, assays and techniques. |
| Specificity Statement: | The antibody is specific for human, mouse and simian IL-25. IL-25 is a cytokine that belongs to the IL-17 cytokine family and is secreted by type 2 helper T cells and mast cells. IL-25 induces the production of other cytokines, including IL-4, IL-5 and IL-13, in multiple tissues and stimulates the expansion of eosinophils. |
| Application Notes: | The original antibody could neutralize recombinant human IL-25 activity in HT-29 cells; the affinity of the antibody for IL-25 were measured using Surface Plasma Resonance (Kd = 24 pM). |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |