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Mfg Part Number

Ab04168-23.0

Vector Labs Ab04168-23.0 Anti-Capsular antigen [P2I67], Rabbit IgG, kappa (100 μg)

VECTOR LABS

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Quick Overview

The original antibody was generated by immunizing mice with various antigen preparations of B. pseudomallei (ATCC 23343). Later on phage display technique was used to generate scFv version of this antibody.

$570.70

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Description

Product Class: Purified
Clone ID: P2I67
Synonyms: surface capsule antigen; Burkholderia mallei; BM; glanders; Burkholderia pseudomallei; BP; Burkholderia spp; melioidosis; Whitmore’s disease
Amount: 100 μg
Application Codes Clone: ELISA
Shipping Temperature: Wet Ice
Buffer Composition: PBS with 0.02% Proclin 300.
Original Format: scFv
Storage Temperature: Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C.
Chimeric Use Statement: This full-length, chimeric rabbit antibody was made using the variable domain sequences of the original Mouse scFv format, for improved compatibility with existing reagents, assays and techniques.
Specificity Statement: This antibody binds surface capsular antigens of Burkholderia pseudomallei (BP), a causative agent of melioidosis, is a gram-negative, facultative anaerobic, motile bacillus commonly found in the soil and stagnant waters. BP infection is often due to either direct inoculation into wounds and skin abrasions or inhalation of contaminated materials. Recently, BP has been recognized as a major cause of community-acquired septicemia, resulting in significant mortality. This antibody also cross reacts with surface capsular antigens of Burkholderia mallei. B. mallei (BM), a host-adapted pathogen that does not normally persist in nature, causes glanders in horse. Some studies indicated that BM is highly infectious in humans by aerosol route.
Application Notes: This antibody can be used for the detection of capsular antigens of Burkholderia pseudomallei and Burkholderia mallei in a sample using ELISA. The binding affinity of the antibody against B. pseudomallei was measured (0.859 at OD405nm) (Kim et al., 2011; PMID: 21172353).

Product Class:	Purified
Clone ID:	P2I67
Synonyms:	surface capsule antigen; Burkholderia mallei; BM; glanders; Burkholderia pseudomallei; BP; Burkholderia spp; melioidosis; Whitmore’s disease
Amount:	100 μg
Application Codes Clone:	ELISA
Shipping Temperature:	Wet Ice
Buffer Composition:	PBS with 0.02% Proclin 300.
Original Format:	scFv
Storage Temperature:	Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C.
Chimeric Use Statement:	This full-length, chimeric rabbit antibody was made using the variable domain sequences of the original Mouse scFv format, for improved compatibility with existing reagents, assays and techniques.
Specificity Statement:	This antibody binds surface capsular antigens of Burkholderia pseudomallei (BP), a causative agent of melioidosis, is a gram-negative, facultative anaerobic, motile bacillus commonly found in the soil and stagnant waters. BP infection is often due to either direct inoculation into wounds and skin abrasions or inhalation of contaminated materials. Recently, BP has been recognized as a major cause of community-acquired septicemia, resulting in significant mortality. This antibody also cross reacts with surface capsular antigens of Burkholderia mallei. B. mallei (BM), a host-adapted pathogen that does not normally persist in nature, causes glanders in horse. Some studies indicated that BM is highly infectious in humans by aerosol route.
Application Notes:	This antibody can be used for the detection of capsular antigens of Burkholderia pseudomallei and Burkholderia mallei in a sample using ELISA. The binding affinity of the antibody against B. pseudomallei was measured (0.859 at OD405nm) (Kim et al., 2011; PMID: 21172353).

Specifications

More Information
Brand	Vector Labs
UNSPSC	12161500

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