Mfg Part Number
Ab04173-10.3
Vector Labs Ab04173-10.3 Anti-FLNB [SH7], Human IgG1, Fc Silent™, kappa (100 μg)
Quick Overview
The original antibody was generated by immunizing mice with FLNB antigen.
$570.70
Order will ship within 1-3 business days
| Product Class: | Purified |
|---|---|
| Clone ID: | SH7 |
| Heavy Chain Modification: | Fc Silent™ |
| Synonyms: | Fh1; FLN-B; filamin B; Filamin-B; ABP-278; ABP-280 homolog; Actin-binding-like protein; Beta-filamin; Filamin homolog 1; Filamin-3; Thyroid autoantigen; Truncated actin-binding protein; Truncated ABP |
| Amount: | 100 μg |
| Application Codes Clone: | ELISA; BLI |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | IgG2b |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Chimeric Use Statement: | This chimeric human antibody was made using the variable domain sequences of the original Mouse IgG2b format, for improved compatibility with existing reagents, assays and techniques. |
| Specificity Statement: | The antibody is specific for FLNB. FLNB is a cytoplasmic protein which in humans is encoded by the FLNB gene. FLNB regulates intracellular communication and signalling by cross-linking the protein actin to allow direct communication between the cell membrane and cytoskeletal network, to control and guide proper skeletal development. |
| Application Notes: | The specificity of the original format of the antibody was confirmed by ELISA analysis. The binding kinetics of the antibody to the full length FLNA protein was measured by BLI (Kd= 1 nM) (WO2018085441A1). |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |