Mfg Part Number
Ab04200-23.159
Vector Labs Ab04200-23.159 Anti-toxin A [A20.1], Rabbit IgG-Fc Fusion, (100 μg)
Quick Overview
The original antibody was generated by immunizing a llama with recombinant RBD fragments TcdA-RBD-f1 and TcdB-RBD-f1, followed by phage display library construction and panning against TcdA-RBD-f1.
$570.70
Order will ship within 1-3 business days
| Product Class: | Purified |
|---|---|
| Clone ID: | A20.1 |
| Synonyms: | TcdA; EC:3.4.22 |
| Amount: | 100 μg |
| Application Codes Clone: | SPR; BLI; ELISA; neutralizing |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | VHH |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Chimeric Use Statement: | This chimeric rabbit antibody was made using the variable domain sequences of the original Llama VHH format, for improved compatibility with existing reagents, assays and techniques. |
| Specificity Statement: | The antibody is specific for toxin A of Clostridium difficile. It recognises a conformational epitope on native C. difficile toxin. |
| Application Notes: | The specificity of the original format of the antibody to TcdA was confirmed by ELISA analysis. The binding affinity of the original format of the antibody was measured by surface plasmon resonance (Kd= 2 nM). Human lung fibroblast (HLF) cytotoxicity assay was used to determine whether the original format of the antibody could neutralize TcdA-induced HLF cell rounding. The antibody showed neutralizing activity to TcdA (US9771416B2). |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |