Mfg Part Number
Ab04200-34.11-BS
Vector Labs Ab04200-34.11-BS Anti-toxin A [A20.1], Camelid VHH, His-tagged, (1 mg)
Quick Overview
The original antibody was generated by immunizing a llama with recombinant RBD fragments TcdA-RBD-f1 and TcdB-RBD-f1, followed by phage display library construction and panning against TcdA-RBD-f1.
$5,162.30
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| Product Class: | Purified |
|---|---|
| Clone ID: | A20.1 |
| Heavy Chain Modification: | His-tagged |
| Synonyms: | TcdA; EC:3.4.22 |
| Amount: | 1 mg |
| Application Codes Clone: | SPR; BLI; ELISA; neutralizing |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS only. |
| Original Format: | VHH |
| Storage Temperature: | Store at 4⁰C for up to 3 months. Note, this antibody is provided without added preservatives, it is therefore recommed this antibody be handled under sterile conditions. For longer storage, aliquot and store at -20⁰C. |
| Specificity Statement: | The antibody is specific for toxin A of Clostridium difficile. It recognises a conformational epitope on native C. difficile toxin. |
| Application Notes: | The specificity of the original format of the antibody to TcdA was confirmed by ELISA analysis. The binding affinity of the original format of the antibody was measured by surface plasmon resonance (Kd= 2 nM). Human lung fibroblast (HLF) cytotoxicity assay was used to determine whether the original format of the antibody could neutralize TcdA-induced HLF cell rounding. The antibody showed neutralizing activity to TcdA (US9771416B2). |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |