Mfg Part Number
Ab04312-10.3
Vector Labs Ab04312-10.3 Anti-MUC-1 [VU-11E2], Human IgG1, Fc Silent™, kappa (100 μg)
Quick Overview
The original antibody was raised by immunizing a mouse with live cells of human breast cancer cell line ZR-75-1.
$570.70
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| Product Class: | Purified |
|---|---|
| Clone ID: | VU-11E2 |
| Heavy Chain Modification: | Fc Silent™ |
| Synonyms: | PEM; EMA; PUM; KL-6; PEMT; CA 15-3; H23AG; Mucin-1; Episialin; Tumor-associated mucin; Polymorphic epithelial mucin; Peanut-reactive urinary mucin; Cancer antigen 15-3; Carcinoma-associated mucin; Breast carcinoma-associated antigen DF3; Tumor-associated epithelial membrane antigen |
| Amount: | 100 μg |
| Application Codes Clone: | ELISA |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | IgG1 |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Chimeric Use Statement: | This is a reformatted human IgG1 Fc Silent Fc Silent™ antibody, based on the original human IgG1 format, created for improved compatibility with existing reagents, assays and techniques. |
| Specificity Statement: | This antibody is specific for the 7-mer TSAPDTR of the MUC1 tandem repeat. |
| Application Notes: | The original antibody was used for an ELISA on different peptides of MUC-1 both glycosylated and unglycosylated, here they determined the epitope of the antibody, it was discovered that the epitope is the 7-mer TSAPDTR of the MUC1 tandem repeat (Karsten et al., 2004; PMID:15115750, Matsushita et al., 2014; PMID:24246952, Guillen-Poza et al., 2020; PMID:32672464). |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |