Vector Labs Ab04350-1.1 Anti-MUC-1 [VU-4H5 ], Mouse IgG1, kappa (100 μg) Centrifuge Bundle Savings at Sycamore Life Sciences

Description

Product Class: Purified
Clone ID: VU-4H5
Synonyms: Mucin-1; CD227; Breast carcinoma-associated antigen DF3; Cancer antigen 15-3; CA 15-3; Carcinoma-associated mucin; Episialin; H23AG; Krebs von den Lungen-6; KL-6; PEMT; Peanut-reactive urinary mucin; PUM; Polymorphic epithelial mucin; PEM; Tumor-associated epithelial membrane antigen; EMA; Tumor-associated mucin; VU4H5
Amount: 100 μg
Application Codes Clone: FC; WB; IF; IHC
Shipping Temperature: Wet Ice
Buffer Composition: PBS with 0.02% Proclin 300.
Original Format: IgG1
Storage Temperature: Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C.
Specificity Statement: This antibody specifically binds to the core protein epitopes within the VNTR domain of human Muc-1 (PMID: 9422085). MUC-1 is a tumor associated antigen expressed on many multiple myelomas, breast and ovarian cancer cells. This antibody does not show reactivity towards fibroblasts, lymphoblastoid cells, and a large number of epithelial cell lines of non-breast origin.
Application Notes: This antibody was used for the flow cytometric analysis of mucin-1 core protein expressed on human multiple myeloma (ARH77, OCI My-5, RPMI 8226, and S6B45), breast cancer (MCF.7 and ZR-75), and ovarian cancer (OVC.3 and 36M) cell lines. This antibody was also used in the phenotypic analysis of cancer patients PBMC cells using immunofluorescence (PMID: 9949172). This antibody was used in the western blot analysis of cell lysates obtained from human MM (S6B45 and RPMI 8226) and prostate cancer (DU145) (PMID: 12090474). This antibody was also used to staining of mucin-1 peptide core uncovered due to aberrantly O-glycosylated tandem repeat region of tumor MUC1 (PMID: 12090474). This antibody was also used in immunohistochemical study of co-expression of hypoglycosylated MUC1 with p-p65 and EzH2 in colon adenocarcinoma (PMID: 29285251).

Product Class:	Purified
Clone ID:	VU-4H5
Synonyms:	Mucin-1; CD227; Breast carcinoma-associated antigen DF3; Cancer antigen 15-3; CA 15-3; Carcinoma-associated mucin; Episialin; H23AG; Krebs von den Lungen-6; KL-6; PEMT; Peanut-reactive urinary mucin; PUM; Polymorphic epithelial mucin; PEM; Tumor-associated epithelial membrane antigen; EMA; Tumor-associated mucin; VU4H5
Amount:	100 μg
Application Codes Clone:	FC; WB; IF; IHC
Shipping Temperature:	Wet Ice
Buffer Composition:	PBS with 0.02% Proclin 300.
Original Format:	IgG1
Storage Temperature:	Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C.
Specificity Statement:	This antibody specifically binds to the core protein epitopes within the VNTR domain of human Muc-1 (PMID: 9422085). MUC-1 is a tumor associated antigen expressed on many multiple myelomas, breast and ovarian cancer cells. This antibody does not show reactivity towards fibroblasts, lymphoblastoid cells, and a large number of epithelial cell lines of non-breast origin.
Application Notes:	This antibody was used for the flow cytometric analysis of mucin-1 core protein expressed on human multiple myeloma (ARH77, OCI My-5, RPMI 8226, and S6B45), breast cancer (MCF.7 and ZR-75), and ovarian cancer (OVC.3 and 36M) cell lines. This antibody was also used in the phenotypic analysis of cancer patients PBMC cells using immunofluorescence (PMID: 9949172). This antibody was used in the western blot analysis of cell lysates obtained from human MM (S6B45 and RPMI 8226) and prostate cancer (DU145) (PMID: 12090474). This antibody was also used to staining of mucin-1 peptide core uncovered due to aberrantly O-glycosylated tandem repeat region of tumor MUC1 (PMID: 12090474). This antibody was also used in immunohistochemical study of co-expression of hypoglycosylated MUC1 with p-p65 and EzH2 in colon adenocarcinoma (PMID: 29285251).

Specifications

More Information
Brand	Vector Labs
UNSPSC	12161500

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