Mfg Part Number
Ab04361-10.3
Vector Labs Ab04361-10.3 Anti-collagen I [AFA], Human IgG1, Fc Silent™, kappa (100 μg)
Quick Overview
The original antibody was generated by immunizing mice with α2Ct.
$570.70
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| Product Class: | Purified |
|---|---|
| Clone ID: | AFA |
| Heavy Chain Modification: | Fc Silent™ |
| Synonyms: | CTTR1; anti-fibrotic antibody; Collagen alpha-1(I) chain; Alpha-1 type I collagen |
| Amount: | 100 μg |
| Application Codes Clone: | Blocking |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | IgA |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Chimeric Use Statement: | This chimeric human antibody was made using the variable domain sequences of the original Mouse IgA format, for improved compatibility with existing reagents, assays and techniques. |
| Specificity Statement: | The antibody is specific for the C-terminal telopeptide region of human collagen I. |
| Application Notes: | The original antibody could block the binding activity of the C-terminal telopeptide region of human collagen I. Biosensor assays of binding interactions of the original format and the Fab fragment of the antibody with procollagen I and the α2Ct were measured (Kd = 663pM for the original antibody and 268nM for the Fab fragment and 21pM for the original antibody and 57nM for the Fab fragment for procollagen and α2Ct respectively) (US20200048333A1). |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |