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Mfg Part Number

Ab04368-23.159

Vector Labs Ab04368-23.159 Anti-CXCR4 [14D09], Rabbit IgG-Fc Fusion, (100 μg)

VECTOR LABS

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Vector Labs Ab04368-23.159 Anti-CXCR4 [14D09], Rabbit IgG-Fc Fusion, (100 μg)

$570.70

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Description

Product Class: Purified
Clone ID: 14D09
Synonyms: CXC-R4; CXCR-4; C-X-C chemokine receptor type 4; fusin; CD184; 2S201E; FB22; HM89; HSY3RR; LAP-3; LAP3; LCR1; LESTR; NPY3R; NPYR; NPYRL; NPYY3R; WHIM; WHIMS; WHIMS1; Leukocyte-derived seven transmembrane domain receptor
Amount: 100 μg
Application Codes Clone: ELISA; FC
Shipping Temperature: Wet Ice
Buffer Composition: PBS with 0.02% Proclin 300.
Original Format: VHH
Storage Temperature: Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C.
Chimeric Use Statement: This chimeric rabbit antibody was made using the variable domain sequences of the original Alpaca VHH format, for improved compatibility with existing reagents, assays and techniques.
Specificity Statement: This antibody is specific for CXCR4.
Application Notes: The binding of the original version of this antibody (VHH) to CXCR4-expressing viral lipoparticles was characterized in an ELISA. Furthermore, it was analyzed for its ability to compete with the ligand CXCL12 (or SDF-1a) for receptor binding by displacement of biotinylated SDF-1 on Caki-CXCR4 cells in flow cytometry. This antibody exhibited medium affinity to its target (EC₅₀/kD of 1 < x ≤ 10 nM) and a ligand inhibition (IC₅₀ 1 < x < 10 nM). In its bi-specific construction with clone 57A07, it served a functional role (US20220242958).

Product Class:	Purified
Clone ID:	14D09
Synonyms:	CXC-R4; CXCR-4; C-X-C chemokine receptor type 4; fusin; CD184; 2S201E; FB22; HM89; HSY3RR; LAP-3; LAP3; LCR1; LESTR; NPY3R; NPYR; NPYRL; NPYY3R; WHIM; WHIMS; WHIMS1; Leukocyte-derived seven transmembrane domain receptor
Amount:	100 μg
Application Codes Clone:	ELISA; FC
Shipping Temperature:	Wet Ice
Buffer Composition:	PBS with 0.02% Proclin 300.
Original Format:	VHH
Storage Temperature:	Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C.
Chimeric Use Statement:	This chimeric rabbit antibody was made using the variable domain sequences of the original Alpaca VHH format, for improved compatibility with existing reagents, assays and techniques.
Specificity Statement:	This antibody is specific for CXCR4.
Application Notes:	The binding of the original version of this antibody (VHH) to CXCR4-expressing viral lipoparticles was characterized in an ELISA. Furthermore, it was analyzed for its ability to compete with the ligand CXCL12 (or SDF-1a) for receptor binding by displacement of biotinylated SDF-1 on Caki-CXCR4 cells in flow cytometry. This antibody exhibited medium affinity to its target (EC₅₀/kD of 1 < x ≤ 10 nM) and a ligand inhibition (IC₅₀ 1 < x < 10 nM). In its bi-specific construction with clone 57A07, it served a functional role (US20220242958).

Specifications

More Information
Brand	Vector Labs
UNSPSC	12161500

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