Mfg Part Number
Ab04370-34.11-BS
Vector Labs Ab04370-34.11-BS Anti-IL-3Ra [57A07], Camelid VHH, His-tagged, (1 mg)
Quick Overview
Vector Labs Ab04370-34.11-BS Anti-IL-3Ra [57A07], Camelid VHH, His-tagged, (1 mg)
$5,162.30
Order will ship within 1-3 business days
| Product Class: | Purified |
|---|---|
| Clone ID: | 57A07 |
| Heavy Chain Modification: | His-tagged |
| Synonyms: | CD123; IL3R; IL3RAY; IL3RX; IL3RY; hIL-3Ra; interleukin 3 receptor subunit alpha; IL-3 receptor subunit alpha; IL-3R subunit alpha; IL-3R-alpha |
| Amount: | 1 mg |
| Application Codes Clone: | ELISA; FACS |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS only. |
| Original Format: | VHH |
| Storage Temperature: | Store at 4⁰C for up to 3 months. Note, this antibody is provided without added preservatives, it is therefore recommed this antibody be handled under sterile conditions. For longer storage, aliquot and store at -20⁰C. |
| Specificity Statement: | This antibody is specific for the alpha subunit of IL-3R |
| Application Notes: | The binding of the original version of this antibody (VHH) to IL3-Ra-expressing viral lipoparticles was characterized in an ELISA (KD 0.783 nM). In a FACS binding assay, this antibody exhibited an EC50 of 0.66 nM, 1.3 nM, and 0.24 nM for MOLM-13, THP-1, and HEK-IL-R3a, respectively, and an IC50 of 1.20 nM in competition against clone 7G3. In its bi-specific constructions with clones 14D09 and 281F12, it served as an anchor (US20220242958). |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |