Mfg Part Number
Ab04371-23.159
Vector Labs Ab04371-23.159 Anti-IL-3Ra [55A01], Rabbit IgG-Fc Fusion, (100 μg)
Quick Overview
Vector Labs Ab04371-23.159 Anti-IL-3Ra [55A01], Rabbit IgG-Fc Fusion, (100 μg)
$570.70
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| Product Class: | Purified |
|---|---|
| Clone ID: | 55A01 |
| Synonyms: | CD123; IL3R; IL3RAY; IL3RX; IL3RY; hIL-3Ra; interleukin 3 receptor subunit alpha; IL-3 receptor subunit alpha; IL-3R subunit alpha; IL-3R-alpha |
| Amount: | 100 μg |
| Application Codes Clone: | ELISA; FACS |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | VHH |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Chimeric Use Statement: | This chimeric rabbit antibody was made using the variable domain sequences of the original Alpaca VHH format, for improved compatibility with existing reagents, assays and techniques. |
| Specificity Statement: | This antibody is specific for the alpha subunit of IL-3R |
| Application Notes: | The binding of the original version of this antibody (VHH) to IL3-Ra-expressing viral lipoparticles was characterized in an ELISA (KD 17.1 nM). In a FACS binding assay, this antibody exhibited an EC50 of 8.2 nM, 11 nM, and 1.1 nM for MOLM-13, THP-1, and HEK-IL-R3a, respectively, and an IC50 of 40.0 nM in competition against clone 7G3. In its bi-specific constructions with clones 14D09 and 281F12, it served as an anchor (US20220242958). |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |