Mfg Part Number
Ab04373-1.1
Vector Labs Ab04373-1.1 Anti-Galectin 9 [1G3], Mouse IgG1, kappa (100 μg)
Quick Overview
The original antibody was generated by immunizing BALB/c mice with a recombinant c-terminus galectin-9 (residues 191 to 355 of the galectin-9 long isoform).
$570.70
Order will ship within 1-3 business days
| Product Class: | Purified |
|---|---|
| Clone ID: | 1G3 |
| Synonyms: | Galectin-9; Gal-9; LGALS9; Ecalectin; Tumor antigen HOM-HD-21 |
| Amount: | 100 μg |
| Application Codes Clone: | ELISA; WB; IHC; Functional assays; Neutralization; Blocking |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | IgG1 |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Specificity Statement: | This antibody is specific for human Gal-9 but exhibits cross-binding of murine Gal-9. |
| Application Notes: | The binding and binding specificity of the original format of this antibody to c-terminus Gal-9 were assessed via ELISA. Epitope mapping was also done using ELISA. Furthermore, this antibody was successfully used in WB and IHC assays (Barjon et al., 2012; PMID: 22805533). An scFv-CAR version of this antibody with therapeutic potential was developed and described (US20230295564A1). This antibody was successfully used to neutralize LGALS9 in a study focused on pancreatic neoplastic lesions (Quilbe et al., 2023; PMID: 38098486). This antibody was used in a T lymphocyte proliferation assay, specifically in assessing the immunomodulatory properties of extracellular vesicles (C15SEVs) derived from nasopharyngeal carcinoma and recombinant Galectin-9S. In this assay, the antibody was used to block the impact of C15SEVs and recombinant Galectin-9 on peripheral blood mononuclear cells (Lefebvre et al., 2023; PMID: 38117000). |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |