Mfg Part Number
Ab04376-1.1
Vector Labs Ab04376-1.1 Anti-M-CSF [5H4], Mouse IgG1, kappa (100 μg)
Quick Overview
Vector Labs Ab04376-1.1 Anti-M-CSF [5H4], Mouse IgG1, kappa (100 μg)
$570.70
Order will ship within 1-3 business days
| Product Class: | Purified |
|---|---|
| Clone ID: | 5H4 |
| Synonyms: | CSF-1; MCSF; PG-M-CSF; Lanimostim; Macrophage colony-stimulating factor; Macrophage colony-stimulating factor 1; Proteoglycan macrophage colony-stimulating factor |
| Amount: | 100 μg |
| Application Codes Clone: | SPR; Neutralizing |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | IgG1 |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Specificity Statement: | The antibody is specific for M-CSF. The antibody binds to a linear epitope represented by ITFEFVDQE, amino acids 65-73 of M-CSF. |
| Application Notes: | The binding properties of the original format of the antibody were analyzed using SPR analyses (Kd = 3 nM). The antibody could neutralize human M-CSF activity, as measured by a proliferation assay with M-NFS-60 cell line. Further, the Fab fragment of the antibody was able to neutralize human M-CSF activity, but with less potency. The humanized variant of the antibody was constructed (EP1913028B1). |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |