Mfg Part Number
Ab04378-10.3
Vector Labs Ab04378-10.3 Anti-M-CSF [MC3], Human IgG1, Fc Silent™, kappa (100 μg)
Quick Overview
The original antibody was generated by immunizing Balb/C mice with recombinant human M-CSF.
$570.70
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| Product Class: | Purified |
|---|---|
| Clone ID: | MC3 |
| Heavy Chain Modification: | Fc Silent™ |
| Synonyms: | CSF-1; MCSF; PG-M-CSF; Lanimostim; Macrophage colony-stimulating factor; Macrophage colony-stimulating factor 1; Proteoglycan macrophage colony-stimulating factor |
| Amount: | 100 μg |
| Application Codes Clone: | SPR; Neutralizing |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | IgG1 |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Chimeric Use Statement: | This chimeric human antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques. |
| Specificity Statement: | The antibody is specific for M-CSF. The antibody binds to a linear epitope represented by ITFEFVDQE amino acids 65-73 of M-CSF. |
| Application Notes: | The binding properties of the original format of the antibody were analyzed using SPR analyses (Kd = 0.27 nM). The antibody could neutralize human M-CSF activity, as measured by a proliferation assay with M-NFS-60 cell line (EP1913028B1). |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |