Mfg Part Number
Ab04379-23.0
Vector Labs Ab04379-23.0 Anti-M-CSF [252], Rabbit IgG, kappa (100 μg)
Quick Overview
The original format of the antibody was generated by immunizing transgenic mice with human M-CSF.
$570.70
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| Product Class: | Purified |
|---|---|
| Clone ID: | 252 |
| Synonyms: | CSF-1; MCSF; PG-M-CSF; Lanimostim; Macrophage colony-stimulating factor; Macrophage colony-stimulating factor 1; Proteoglycan macrophage colony-stimulating factor |
| Amount: | 100 μg |
| Application Codes Clone: | SPR; Inhibition |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | IgG1 |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Chimeric Use Statement: | This chimeric rabbit antibody was made using the variable domain sequences of the original Human IgG1 format, for improved compatibility with existing reagents, assays and techniques. |
| Specificity Statement: | The antibody is specific for M-CSF. |
| Application Notes: | The original format of the antibody inhibited mouse monocytic cell proliferation in response to M-CSF. Further, the IC50 for inhibition of mouse nonocytic cell proliferation was determined for the antibody (IC50 = 86.7 nM). The binding properties of the original format of the antibody were analyzed using SPR analysis (Kd= 0.13 pM) (US7326414B2). |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |