Mfg Part Number
Ab04403-10.0
Vector Labs Ab04403-10.0 Anti-Genome polyprotein [NA9D7], Human IgG1, kappa (100 μg)
Quick Overview
The original antibody was raised by immunizing a mouse with CVA16.
$570.70
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| Product Class: | Purified |
|---|---|
| Clone ID: | NA9D7 |
| Synonyms: | P1; 18A7 |
| Amount: | 100 μg |
| Application Codes Clone: | ELISA; neutralization; in vitro |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | Fab |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Chimeric Use Statement: | This chimeric human antibody was made using the variable domain sequences of the original Mouse Fab format, for improved compatibility with existing reagents, assays and techniques. |
| Specificity Statement: | This antibody is specific for the inner surface of the canyon of CVA16. |
| Application Notes: | The original antibody was used for a neutralization assay against CVA16 in human rhabdomyosarcoma (He et al., 2020; PMID:32027857). Further an ELISA was performed on 16 strains of CVA16 (He et al., 2020; PMID:32027857), and on CVA16 (Cu et al., 2021; PMID:32750255). The structure of this antibody was determined using cryo-EM (He et al., 2020; PMID:32027857). A bispecific version of this antibody was used for an immunofluorescence assay on EV71- and CA16-infected cells. Furthermore a bispecific version of this antibody was used for an ELISA on EV71 or CA16. Finally the bispecific version of this antibody was used for neutralization (Zhou et al., 2019; PMID:30419253). |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |