Mfg Part Number
Ab04424-1.29
Vector Labs Ab04424-1.29 Anti-Genome polyprotein [C5], Mouse Fab fragment, His-Tagged, kappa (100 μg)
Quick Overview
The original antibody was raised by immunizing a mouse with human rhinovirus 14.
$692.90
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| Product Class: | Purified |
|---|---|
| Clone ID: | C5 |
| Heavy Chain Modification: | His-Tagged |
| Synonyms: | P1; Capsid protein VP3; Virion protein 3 |
| Amount: | 100 μg |
| Application Codes Clone: | Neutralization |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | Fab |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Chimeric Use Statement: | This reformatted mouse antibody was made using the variable domain sequences of the original Mouse Fab format, for improved compatibility with existing reagents, assays and techniques. |
| Specificity Statement: | This antibody is specific for capsid protein VP3, NIm-III site of Human rhinovirus 14. |
| Application Notes: | The structure of the original antibody bound to its antigen was determined using cryo-EM. Further the original antibody was used for both a preattachment neutralizing assay and a postattachment neutralization assay on HeLa-H1 cell monolayers. The antibody showed the ability to neutralize RV-B14 in both assays. The antibody was able to trigger genome release in the virus (Dong et al., 2017; PMID:28696310). |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |