Mfg Part Number
Ab04427-23.0
Vector Labs Ab04427-23.0 Anti-env, Envelope glycoprotein gp160 [Fab 58.2], Rabbit IgG, kappa (100 μg)
Quick Overview
The original antibody was raised by immunizing a mouse with a 40 amino-acid cyclical peptide containing the entire V3 sequence of HIV-1
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| Product Class: | Purified |
|---|---|
| Clone ID: | Fab 58.2 |
| Synonyms: | gp120; Glycoprotein 120; Surface protein gp120 |
| Amount: | 100 μg |
| Application Codes Clone: | ELISA; neutralization; in vitro; crystallography |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | IgG1 |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Chimeric Use Statement: | This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques. |
| Specificity Statement: | This antibody is specific for an epitope of envelope glycoprotein gp160 containing the HIGPGRAF sequence |
| Application Notes: | The original antibody was used for an ELISA on repligen peptides containing V3 sequences. Further this antibody was used for a neutralization assay using 3 different HIV strains on CEM-SS cells. Here it was able to neutralize specific HIV strains (White-Scharf et al., 1993; PMID:7685962). The structure of the original antibody was determined using x-ray crystallography (Stanfield et al., 1999; PMID:10368281). This antibody was used for panning against a peptide display library (Jellis et al., 1993; PMID:7506691). |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |