Mfg Part Number
Ab04428-3.3
Vector Labs Ab04428-3.3 Anti-Envelope glycoprotein gp160 [0.5beta], Mouse IgG2b, Fc Silent™, kappa (100 μg)
Quick Overview
The original antibody was raised by immunizing a mouse with the glycoprotein fraction prepared from H9/HTLV IIIB cell extracts.
$570.70
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| Product Class: | Purified |
|---|---|
| Clone ID: | 0.5beta |
| Heavy Chain Modification: | Fc Silent™ |
| Synonyms: | env; Env polyprotein; Envelope glycoprotein gp160 |
| Amount: | 100 μg |
| Application Codes Clone: | ELISA; WB; neutralization |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | IgG2b |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Specificity Statement: | This antibody is specific forth V3 loop of the envelope glycoprotein gp160. |
| Application Notes: | The original version of this antibody was used for an ELISA on a synthetic 20 amino acid peptide (308-327) based on the sequence of the RP135 region of gp120 from HIV-IIIB (Maeda et al., 1991; PMID:1873503). This antibody was used for a western blot on HTLV-IIIB antigens (Matsushita et al., 1988; PMID:2452899), and on Purified HTLV-IIIB (Skinner et al., 1988; PMID:2456088). The NMR structure of this antibody was determined (Tugarinov et al., 2000; PMID:10801487). The ability of this antibody to neutralize a cell-free HIV infection of H9 cells was assayed. It was indeed able to prevent this infection (Matsushita et al., 1988; PMID:2452899). This antibody was also able to neutralize the HIV infection of AA-5 cells (Skinner et al., 1988; PMID:2456088). This antibody was able to prevent HIV infection in chimpanzees in vivo (Emini et al., 1992; PMID:1741059). |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |