Mfg Part Number
Ab04437-23.0

Vector Labs Ab04437-23.0 Anti-Cell surface-binding protein D8L [LA5], Rabbit IgG, kappa (100 μg)

Quick Overview
The original antibody was raised by immunizing a mouse with VACV.
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Product Class:Purified
Clone ID:LA5
Synonyms:OPG105; D8L; VACWR113; Carbonic anhydrase homolog; Cell surface-binding protein OPG105
Amount:100 μg
Application Codes Clone:neutralization; ELISA; SPR
Shipping Temperature:Wet Ice
Buffer Composition:PBS with 0.02% Proclin 300.
Original Format:IgG2a
Storage Temperature:Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C.
Chimeric Use Statement:This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG2a format, for improved compatibility with existing reagents, assays and techniques.
Specificity Statement:This antibody is specific for protein D8 of the vaccinia virus. It binds above the CS-E binding crevice
Application Notes:The original version of this antibody was used for ELISA on recombinant D8 protein. The binding strength of this antibody was also determined using surface plasmon resonance on VAVC D8 (Matho et al., 2012; PMID:22623786). The original antibody was used for neutralization of a intracellular mature virion. It showed that is was only able to neutralize the intracellular mature virion in the present of complement (Matho et al., 2018; PMID:29123031).
More Information
Brand Vector Labs
UNSPSC 12161500