Mfg Part Number
Ab04445-10.29
Vector Labs Ab04445-10.29 Anti- Fusion glycoprotein F0 [PIA174], Human Fab fragment, His-Tagged, kappa (100 μg)
Quick Overview
The original antibody was raised by isolating it from a B cell culture supernatant.
$692.90
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| Product Class: | Purified |
|---|---|
| Clone ID: | PIA174 |
| Heavy Chain Modification: | His-Tagged |
| Synonyms: | F; Protein F; Human respirovirus 3 |
| Amount: | 100 μg |
| Application Codes Clone: | ELISA; in vitro; neutralization; SPR |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | Fab |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Chimeric Use Statement: | This reformatted human antibody was made using the variable domain sequences of the original Human Fab format, for improved compatibility with existing reagents, assays and techniques. |
| Specificity Statement: | This antibody is specific for DIII domain of fusion glycoprotein F0 from human respirovirus 3. |
| Application Notes: | The original antibody was used for an ELISA on parainfluenza virus type 3. Further the structure of this antibody was determined using cryo-EM (Stewart-Jones et al., 2018;PMID:30420505). This antibody was used for a plaque reduction assay on Vero cells infected with parental or escape variant of human respirovirus. This antibody was used for a neutralization assay. It showed here that it disrupted the formation of the HN/F complex (Marcink et al., 2023; PMID:36763666). This antibody was used for surface plasmon resonance on LuS-N71-SpyLinked-PIV3 F (Zhang et al., 2020; PMID:33097791). |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |