Mfg Part Number
Ab04452-23.0
Vector Labs Ab04452-23.0 Anti-Envelope glycoprotein H; Envelope glycoprotein L [Fab-RC], Rabbit IgG, kappa (100 μg)
Quick Overview
The original antibody was raised from the white blood cells of a human individual immunized with zoster vaccine.
$570.70
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| Product Class: | Purified |
|---|---|
| Clone ID: | Fab-RC |
| Synonyms: | gH; gL; ORF60; ORF37 |
| Amount: | 100 μg |
| Application Codes Clone: | SPR; IHC; IP; crystallography; neutralization |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | IgG |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Chimeric Use Statement: | This chimeric rabbit antibody was made using the variable domain sequences of the original Human IgG format, for improved compatibility with existing reagents, assays and techniques. |
| Specificity Statement: | This antibody is specific for the combination of gH and gL and does not detect the proteins in isolation. |
| Application Notes: | The original antibody was used for surface plasmon resonance on VZV gHgL. This antibody was used for a neutralization assay. Here is showed it was able to inhibit gB/gHgL-mediated membrane fusion. The structure of this antibody was determined using x-ray crystallography (Xing et al., 2015; PMID:25918416). This antibody was used for immunohistochemistry on fixed and unfixed VZV-infected and control HFL cells. This antibody was also used for a plaque reduction assay on VZV-infected HFL cells. Further this antibody was used for immunoprecipitation on VZV-infected and uninfected HFL cells (Birlea et al., 2013; PMID:23077312). |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |