Mfg Part Number
Ab04490-23.0
Vector Labs Ab04490-23.0 Anti-Fusion glycoprotein F0 [B13], Rabbit IgG, lambda (100 μg)
Quick Overview
The original antibody was raised by immunizing a 10-month-old calf with persistently infected bovine nasal mucosa cell line NM7B.
$570.70
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| Product Class: | Purified |
|---|---|
| Clone ID: | B13 |
| Synonyms: | F; p27; Protein F; Fusion glycoprotein F1; Fusion glycoprotein F2 |
| Amount: | 100 μg |
| Application Codes Clone: | ELISA; SPR; IHC; neutralization; crystallography |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | IgG1 |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Chimeric Use Statement: | This chimeric rabbit antibody was made using the variable domain sequences of the original Cow IgG1 format, for improved compatibility with existing reagents, assays and techniques. |
| Specificity Statement: | This antibody is specific for protein F from the respiratory syncytial virus |
| Application Notes: | The original antibody was used for an ELISA on lysed Vero cells infected with bovine RSV. Further this antibody was used for surface plasmon resonance on F protein. Finally the structure of this antibody was determined using x-ray crystallography (Ren et al., 2019; PMID:31100550). This antibody was used for immunohistochemistry on bovine lung tissue from infected calves. It showed the location of the virus in this experiment. Further this antibody was used for an in vivo neutralization assay, here calves were gives this antibody before they were infected. It showed a decrease in virus titer after 7 days (Thomas et al., 1998; PMID:9534958). |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |