Mfg Part Number
Ab04498-23.0
Vector Labs Ab04498-23.0 Anti-FVIIa DVQ [mAb4F5], Rabbit IgG, kappa (100 μg)
Quick Overview
The original antibody was generated by immunizing mice with FVIIaDVQ.
$570.70
Order will ship within 1-3 business days
| Product Class: | Purified |
|---|---|
| Clone ID: | mAb4F5 |
| Synonyms: | SPCA; Eptacog alfa; Proconvertin; Coagulation factor VII; EC:3.4.21.21; Blood coagulation factor VIIa; Serum prothrombin conversion accelerator |
| Amount: | 100 μg |
| Application Codes Clone: | SPR; Crystallization |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | IgG1 |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Chimeric Use Statement: | This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques. |
| Specificity Statement: | The antibody is specific for FVIIa. In particular, the epitope interacts with the periphery of the hydrophobic pocket. |
| Application Notes: | The binding affinity of original format of the antibody to FVIIaDVQ was measured by surface plasmon resonance (Kd= 32 pM). The crystal structure of the Fab fragment of the antibody was determined (Jiang et al., 2019; PMID: 31294329). |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |