Mfg Part Number
Ab04499-23.0
Vector Labs Ab04499-23.0 Anti-prothrombin [POmAb], Rabbit IgG, kappa (100 μg)
Quick Overview
Vector Labs Ab04499-23.0 Anti-prothrombin [POmAb], Rabbit IgG, kappa (100 μg)
$570.70
Order will ship within 1-3 business days
| Product Class: | Purified |
|---|---|
| Clone ID: | POmAb |
| Synonyms: | EC:3.4.21.5; Coagulation factor II; Prothrombin Open monoclonal Antibody |
| Amount: | 100 μg |
| Application Codes Clone: | SPR; Crystallization |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | IgG1 |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Chimeric Use Statement: | This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques. |
| Specificity Statement: | The antibody is specific for the open form of prothrombin. Its epitope is located in kringle-1, comprising an extended binding interface centered at residues R90-Y93. |
| Application Notes: | The binding affinity of original format of the antibody to prothrombin was measured by surface plasmon resonance. The crystal structure of the Fab fragment of the antibody was determined. The antibody could prolong phospholipid-initiated and diluted Russell viper venom clotting time (Kumar et al., 2024; PMID: 38437497). |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |