Mfg Part Number
Ab04509-34.11
Vector Labs Ab04509-34.11 Anti-TLR3 [132-D4], Camelid VHH, His-tagged, (100 μg)
Quick Overview
The original antibody was generated by immunizing llamas with a cocktail of murine and human Toll-like receptors (TLRs) that contained recombinant human TLR4/MD2, recombinant human TLR3, recombinant murine TLR3, and recombinant murine TLR2/Fc chimera. Peripheral blood mononuclear cells were isolated from the animals' blood for the construction of a phage display library, and the library was panned against the TLRs used for immunization.
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| Product Class: | Purified |
|---|---|
| Clone ID: | 132-D4 |
| Heavy Chain Modification: | His-tagged |
| Synonyms: | Toll-like receptor 3; CD283 |
| Amount: | 100 μg |
| Application Codes Clone: | ELISA; NTRL |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | VHH |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Specificity Statement: | This antibody is specific for mouse TLR3. |
| Application Notes: | The binding specificity of the original version of this antibody (VHH) was tested using ELISA. In a cell-based neutralizing assay with mTLR3-overexpressing HEK cells, an antagonistic effect was observed, as measured by NFκB expression after cell lysis compared to the control group (WO2009138494A2). |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |