Mfg Part Number
Ab04513-23.159
Vector Labs Ab04513-23.159 Anti-TLR4 [133-A1], Rabbit IgG-Fc Fusion, (100 μg)
Quick Overview
The original antibody was generated by immunizing llamas with a cocktail of murine and human Toll-like receptors (TLRs) that contained recombinant human TLR4/MD2, recombinant human TLR3, recombinant murine TLR3, and recombinant murine TLR2/Fc chimera. Peripheral blood mononuclear cells were isolated from the animals' blood for the construction of a phage display library, and the library was panned against the TLRs used for immunization.
$570.70
Order will ship within 1-3 business days
| Product Class: | Purified |
|---|---|
| Clone ID: | 133-A1 |
| Synonyms: | hToll; CD284; Toll-like receptor 4 |
| Amount: | 100 μg |
| Application Codes Clone: | ELISA; NTRL |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | VHH |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Chimeric Use Statement: | This chimeric rabbit antibody was made using the variable domain sequences of the original Llama VHH format, for improved compatibility with existing reagents, assays and techniques. |
| Specificity Statement: | This antibody is specific for human TLR4. |
| Application Notes: | The binding specificity of the original version of this antibody (VHH) was tested using ELISA. In a cell-based neutralizing assay with hTLR4-overexpressing HEK cells, an antagonistic effect was observed, as measured by NFκB expression after cell lysis compared to the control group (WO2009138494A2). |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |