Mfg Part Number
Ab04521-10.0
Vector Labs Ab04521-10.0 Anti-HIV-1 surface protein gp120 [694-D], Human IgG1, lambda (100 μg)
Quick Overview
The original antibody was generated by Epstein-Barr virus transformation of peripheral blood mononuclear cells from HIV-seropositive individuals and screening for reactivity against the rgp120IIIB peptide.
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| Product Class: | Purified |
|---|---|
| Clone ID: | 694-D |
| Synonyms: | Surface protein gp120; Envelope glycoprotein gp160; Env polyprotein |
| Amount: | 100 μg |
| Application Codes Clone: | ELISA; IB; Neutralization |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | IgG1 |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Specificity Statement: | This antibody is specific for the GRAF sequence of the gp120 V3 loop of HIV-1. |
| Application Notes: | The original version of this antibody (human IgG1) was characterized for its specificity and reactivity using ELISA and IB assays. In the ELISA, it reacted with the V3 of HIV strains MN, SF-2, HXB2, RF, WM52, NY5, SC, and CDC4 with an affinity (Kd) of 1.8 µM and 12.0 µM for SF-2 and HXB2, respectively. In an IB, this antibody reacted with gp120HTLV-IIIB. In in vitro neutralization assays, this antibody exhibited neutralizing activity against multiple HIV-1 strains, exhibiting broad reactivity (US5914109A). |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |