Mfg Part Number
Ab04528-10.3
Vector Labs Ab04528-10.3 Anti-Snake venom metalloproteinase TM-3 [SVMP-mc18], Human IgG1, Fc Silent™, kappa (100 μg)
Quick Overview
The original antibody was generated by immunizing BALB/c mice with natural snake venom metalloproteinase TM-3 purified from crude venom of Protobothrops mucrosquamatus.
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| Product Class: | Purified |
|---|---|
| Clone ID: | SVMP-mc18 |
| Heavy Chain Modification: | Fc Silent™ |
| Synonyms: | SVMP; SVMP protein; SVMP TM-3; Atrolysin e; Fibrinlysin; Trimutase; Zinc metalloproteinase/disintegrin |
| Amount: | 100 μg |
| Application Codes Clone: | ELISA; WB |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | IgG1 |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Chimeric Use Statement: | This chimeric human antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques. |
| Specificity Statement: | This antibody reacts specifically with snake venom metalloproteinase (SVMP) TM-3 present in the venom of Protobothrops mucrosquamatus. SVMP is a potent fibrinogenolytic protease which cleaves mainly the alpha chain of fibrinogen (FGA) and slightly the beta (FGB) and the gamma (FGG) chains. It has hemorrhagic activity. |
| Application Notes: | This antibody can be used for the detection of SVMP protein of Trimeresurus mucrosquamatus by ELISA. The binding specifcity of the antibody was further confirmed by detection of the protein in a western blot (CN113832132; PMID: 34899734). |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |