Mfg Part Number
Ab04533-23.0
Vector Labs Ab04533-23.0 Anti-Acetylcholinesterase [Elec410], Rabbit IgG, kappa (100 μg)
Quick Overview
The original antibody was generated by immunizing were mice (Biozzi high-responder strain) with MPT-treated Electrophorus AChE.
$570.70
Order will ship within 1-3 business days
| Product Class: | Purified |
|---|---|
| Clone ID: | Elec410 |
| Synonyms: | AChE; EeAChE; BfAChE; Fab410; Elec-410 |
| Amount: | 100 μg |
| Application Codes Clone: | ELISA; inhibit |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | IgG1 |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Chimeric Use Statement: | This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques. |
| Specificity Statement: | This antibody binds the peripheral site of AChE. |
| Application Notes: | This antibody competes with fasciculin for binding with AChE. The binding affinity of this antibody towards E. electricus AChE was evaluated using ELISA and it was found to be Kd= 0.036 nM. This antibody also inhibits B. fasciatus AChE with an apparent Ki value in the nanomolar range (PMID: 7649165). This antibody was also reported to inhibit Ophiophagus hannah AChE with an IC50 value of ~50 nM (PMID: 9187246). |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |