Mfg Part Number
Ab04539-23.159
Vector Labs Ab04539-23.159 Anti-Aztreonam [AbAb-Aztreo], Rabbit IgG-Fc Fusion, (100 μg)
Quick Overview
The original antibody was generated by immunizing Lama glama with aztreonam conjugated with human serum albumin. The peripheral blood lymphocytes of the llama were used to generate a VHH library and the specific antibody was selected by panning the library against aztreonam-KLH conjugate.
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| Product Class: | Purified |
|---|---|
| Clone ID: | AbAb-Aztreo |
| Synonyms: | Azactam |
| Amount: | 100 μg |
| Application Codes Clone: | ELISA |
| Shipping Temperature: | Wet Ice |
| Origin Pub PMID: | 34931798 |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | VHH |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Chimeric Use Statement: | This chimeric rabbit antibody was made using the variable domain sequences of the original Llama VHH format, for improved compatibility with existing reagents, assays and techniques. |
| Specificity Statement: | This antibody shows reactivity against aztreonam, a synthetic monobactam antibiotic, which is similar to aminoglycosides, it is active mostly against gram-negative, aerobic bacteria. Aztreonam has been used for the treatment of a variety of infections caused by gram-negative pathogens. |
| Application Notes: | The binding characterization of this antibody was done using ELISA. This antibody in combination with an anti-omalizumab antibody E5 was used in the generation of a bispecific antibody for determination of allergy against the aztreonam antibiotic (PMID: 34931798). |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |