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Mfg Part Number

Ab04572-10.159

Vector Labs Ab04572-10.159 Anti-CD9 [Nb16-17], Human IgG1-Fc Fusion, (100 μg)

VECTOR LABS

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Quick Overview

The original antibody was generated by immunizing an alpaca with a CD9-LaFc recombinant fusion protein containing human CD9 (Ser112-lle195) and alpaca LaFc sequence. The peripheral blood lyphocytes from the alpaca were used to generate a phage display library and the actual clone was isolated by panning the library against human CD9-his protein.

$570.70

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Description

Product Class: Purified
Clone ID: Nb16-17
Synonyms: p24; MIC3; MRP-1; GIG2; Tspan-29; TSPAN29; 5H9 antigen; Cell growth-inhibiting gene 2 protein; Leukocyte antigen MIC3; Motility-related protein; Tetraspanin-29
Amount: 100 μg
Application Codes Clone: ELISA
Shipping Temperature: Wet Ice
Buffer Composition: PBS with 0.02% Proclin 300.
Original Format: VHH
Storage Temperature: Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C.
Chimeric Use Statement: This chimeric human antibody was made using the variable domain sequences of the original Alpaca VHH format, for improved compatibility with existing reagents, assays and techniques.
Specificity Statement: This antibody specifically binds an epitope between amino acids 112-195 of human CD9. This protein is an integral membrane protein associated with integrins, which regulates different processes, such as sperm-egg fusion, platelet activation and aggregation, and cell adhesion. Extracellular vesicles (EVs) such as exosomes are important mediators in intercellular communications and play a role in cancer progression and metastasis. Exosomal membranes are enriched in endosome-specific tetraspanins like CD9. EVs have strong potential as blood-based or urine-based biomarkers for the diagnosis, prognostication, and surveillance of cancer.
Application Notes: The binding specificity of this antibody for recombinant his tagged CD9 protein was determined using ELISA (CN117659191).

Product Class:	Purified
Clone ID:	Nb16-17
Synonyms:	p24; MIC3; MRP-1; GIG2; Tspan-29; TSPAN29; 5H9 antigen; Cell growth-inhibiting gene 2 protein; Leukocyte antigen MIC3; Motility-related protein; Tetraspanin-29
Amount:	100 μg
Application Codes Clone:	ELISA
Shipping Temperature:	Wet Ice
Buffer Composition:	PBS with 0.02% Proclin 300.
Original Format:	VHH
Storage Temperature:	Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C.
Chimeric Use Statement:	This chimeric human antibody was made using the variable domain sequences of the original Alpaca VHH format, for improved compatibility with existing reagents, assays and techniques.
Specificity Statement:	This antibody specifically binds an epitope between amino acids 112-195 of human CD9. This protein is an integral membrane protein associated with integrins, which regulates different processes, such as sperm-egg fusion, platelet activation and aggregation, and cell adhesion. Extracellular vesicles (EVs) such as exosomes are important mediators in intercellular communications and play a role in cancer progression and metastasis. Exosomal membranes are enriched in endosome-specific tetraspanins like CD9. EVs have strong potential as blood-based or urine-based biomarkers for the diagnosis, prognostication, and surveillance of cancer.
Application Notes:	The binding specificity of this antibody for recombinant his tagged CD9 protein was determined using ELISA (CN117659191).

Specifications

More Information
Brand	Vector Labs
UNSPSC	12161500

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