Mfg Part Number
Ab04572-34.11-BS
Vector Labs Ab04572-34.11-BS Anti-CD9 [Nb16-17], Camelid VHH, His-tagged, (1 mg)
Quick Overview
The original antibody was generated by immunizing an alpaca with a CD9-LaFc recombinant fusion protein containing human CD9 (Ser112-lle195) and alpaca LaFc sequence. The peripheral blood lyphocytes from the alpaca were used to generate a phage display library and the actual clone was isolated by panning the library against human CD9-his protein.
$5,162.30
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| Product Class: | Purified |
|---|---|
| Clone ID: | Nb16-17 |
| Heavy Chain Modification: | His-tagged |
| Synonyms: | p24; MIC3; MRP-1; GIG2; Tspan-29; TSPAN29; 5H9 antigen; Cell growth-inhibiting gene 2 protein; Leukocyte antigen MIC3; Motility-related protein; Tetraspanin-29 |
| Amount: | 1 mg |
| Application Codes Clone: | ELISA |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS only. |
| Original Format: | VHH |
| Storage Temperature: | Store at 4⁰C for up to 3 months. Note, this antibody is provided without added preservatives, it is therefore recommed this antibody be handled under sterile conditions. For longer storage, aliquot and store at -20⁰C. |
| Specificity Statement: | This antibody specifically binds an epitope between amino acids 112-195 of human CD9. This protein is an integral membrane protein associated with integrins, which regulates different processes, such as sperm-egg fusion, platelet activation and aggregation, and cell adhesion. Extracellular vesicles (EVs) such as exosomes are important mediators in intercellular communications and play a role in cancer progression and metastasis. Exosomal membranes are enriched in endosome-specific tetraspanins like CD9. EVs have strong potential as blood-based or urine-based biomarkers for the diagnosis, prognostication, and surveillance of cancer. |
| Application Notes: | The binding specificity of this antibody for recombinant his tagged CD9 protein was determined using ELISA (CN117659191). |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |