Mfg Part Number
Ab04577-10.3
Vector Labs Ab04577-10.3 Anti-Severe Fever and Thrombocytopenic Syndrome Virus [2D10], Human IgG1, Fc Silent™, kappa (100 μg)
Quick Overview
The original antibody was generated by immunizing BALB/c mice with inactivated SFTS virus antigen. The inactivated virus was obtained by inoculating Vero E6 cells with SFTS virus and culturing the cells for 5-7 days at RT. Later one the cells were treated with Binary Ethylenimine (BEI) to inactivate the virus.
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| Product Class: | Purified |
|---|---|
| Clone ID: | 2D10 |
| Heavy Chain Modification: | Fc Silent™ |
| Synonyms: | SFTSV; SFTS; Glycoprotein N; SFTSV Gn; Envelopment polyprotein; Severe Fever and Thrombocytopenic Syndrome Virus; arthropod-borne phleboviruses |
| Amount: | 100 μg |
| Application Codes Clone: | ELISA |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | IgG2a |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Chimeric Use Statement: | This chimeric human antibody was made using the variable domain sequences of the original Mouse IgG2a format, for improved compatibility with existing reagents, assays and techniques. |
| Specificity Statement: | This antibody binds the severe fever and thrombocytopenic syndrome virus and does not cross react with any other arthropod-borne phleboviruses. Severe Fever with Thrombocytopenia Syndrome (SFTS) is an emerging infectious disease caused by the SFTS virus which is transmitted to humans through the bite of an infected tick. Most patients have symptoms such as fever, low platelet count and leukopenia, and may also have symptoms such as nausea, vomiting, diarrhea, headache, muscle pain, lymphatic enlargement, and bleeding. Recently, first case of human-to-human transmission of SFTS virus was reported in Japan. |
| Application Notes: | This antibody can be used for the detection of SFTS virus in an ELISA. This antibody also be used as a capture antibody in combination with another antibody 3A10 (detection antibody) for detecting SFTS virus in a sandwich ELISA (KR102652753). |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |