Mfg Part Number
Ab04586-1.1
Vector Labs Ab04586-1.1 Anti-CD62L [LAM1-116], Mouse IgG1, kappa (100 μg)
Quick Overview
This original antibody was raised by immunizing a L-selectin deficient mouse with L-selectin.
$570.70
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| Product Class: | Purified |
|---|---|
| Clone ID: | LAM1-116 |
| Synonyms: | SELL; L-selectin; LAM-1; LECAM1; Leukocyte surface antigen Leu-8; Leukocyte adhesion molecule 1; Lymph node homing receptor; CD62 antigen-like family member L; Leukocyte-endothelial cell adhesion molecule 1 |
| Amount: | 100 μg |
| Application Codes Clone: | FC; IP; IF; IHC |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | IgG2c |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Chimeric Use Statement: | This reformatted mouse antibody was made using the variable domain sequences of the original Mouse IgG2c format, for improved compatibility with existing reagents, assays and techniques. |
| Specificity Statement: | This antibody is specific for the natural ligand binding domain of L-selectin. |
| Application Notes: | The original antibody was used for flow cytometry on Holstein calve and sheep leukocytes (Leid et al., 2001; PMID:11290767), on EDTA-anticoagulated guinea pig blood (Fryer et al., 1997; PMID:9109449), an d on plasma samples from rats (Yan et al., 2000; PMID:10803628). This antibody was used for immunoprecipitation of L-selectin from bovine lymphocyte lysates (Leid et al., 2001; PMID:11290767), and on RBL cells (Haribabu et al., 1997; PMID:9153259). This antibody was used to test the effect of the antibody on NF-kappa B activation. It was shown that this antibody could indeed activate NF-kappa B in neutrophils (Turutin et al., 2003; PMID:12586371). This antibody was used for immunohistochemistry on a rat endometriosis model and on tissues of human endometriosis. This antibody was able to show the localization of the protein (Odagiri et al., 2007; PMID:17482182). This antibody was used for immunofluorescence on RBL cells where it showed staining like expected (Haribabu et al., 1997; PMID:9153259). |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |