Mfg Part Number
Ab04594-10.0
Vector Labs Ab04594-10.0 Anti-SOD1 [B12], Human IgG1, lambda (100 μg)
Quick Overview
This antibody was raised from a phage-displayed scFv antibody library
$570.70
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| Product Class: | Purified |
|---|---|
| Clone ID: | B12 |
| Synonyms: | SOD1; SOD1G93A; SOD1 A4V |
| Amount: | 100 μg |
| Application Codes Clone: | WB; in vitro |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | scFv |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Chimeric Use Statement: | This full-length, reformatted human antibody was made using the variable domain sequences of the original Human scFv format, for improved compatibility with existing reagents, assays and techniques. |
| Specificity Statement: | This antibody is specific for misfolded SOD1. |
| Application Notes: | This antibody was used for a western blot on reacted against denatured wt and mt SOD1. It reacted to denatured wt, A4V and G93A SOD1 proteins but not the control SH3 protein. This antibody was used in vitro on NSC cells to determine the effect of the antibody on A4V and G93A mtSOD1 mediated cell death. The antibody has shown the ability to decrease the cell death caused by A4V and G93A mtSOD1 (Ghadge et al., 2014; PMID:23607939). |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |