Mfg Part Number
Ab04595-2.3
Vector Labs Ab04595-2.3 Anti-MuSK [MuSK #13], Mouse IgG2a, Fc Silent™, kappa (100 μg)
Quick Overview
This antibody was raised by immunizing mice with human MuSK.
$570.70
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| Product Class: | Purified |
|---|---|
| Clone ID: | MuSK #13 |
| Heavy Chain Modification: | Fc Silent™ |
| Synonyms: | Muscle-specific kinase receptor; Muscle, skeletal receptor tyrosine-protein kinase; Muscle-specific tyrosine-protein kinase receptor |
| Amount: | 100 μg |
| Application Codes Clone: | in vitro; in vivo |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | IgG2a |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Specificity Statement: | This antibody is specific for human MuSK. |
| Application Notes: | The original antibody was used in vitro to test if it could activate its target. It showed to be a potent MuSK activator. The antibody was also tested in vivo on mice. Here is was shown to localize to the neuromuscular junctions here it increased innervation. This antibody did not show any delay in onset of ALS symptoms (Sengupta-Ghosh et al., 2019; PMID: 30528255). |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |