Mfg Part Number
Ab04597-10.29
Vector Labs Ab04597-10.29 Anti-FGFR-1 [FR1-H7], Human Fab fragment, His-Tagged, kappa (100 μg)
Quick Overview
The original antibody was raised by panning a fab library against FGFR-1(IIIb).
$692.90
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| Product Class: | Purified |
|---|---|
| Clone ID: | FR1-H7 |
| Heavy Chain Modification: | His-Tagged |
| Synonyms: | FLT-2; BFGFR; bFGF-R-1; N-sam; CD331; Proto-oncogene c-Fgr; Fms-like tyrosine kinase 2; Basic fibroblast growth factor receptor 1 |
| Amount: | 100 μg |
| Application Codes Clone: | in vitro |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | Fab |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Chimeric Use Statement: | This reformatted human antibody was made using the variable domain sequences of the original Human Fab format, for improved compatibility with existing reagents, assays and techniques. |
| Specificity Statement: | This antibody is specific for human FGFR-1(IIIb) and FGFR-1(IIIc). |
| Application Notes: | The original antibody was used for a co-culture proliferation assay on HUVEC-Akt cells. It showed a decrease in cell proliferation (Ding et al., 2015; PMID:26116571). This antibody was used for an ELISA on FGFR-1. Here is showed binding to FGFR-1(IIIb) and FGFR-1(IIIc). This antibody was used for immunoprecipitation on FGFR-1. Where it showed similair results to the ELISA. This antibody was used in vivo on nude mice. The effect of the antibody was significant weight reduction within 48 hours (US8263074B2). |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |