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Mfg Part Number

Ab04622-10.3

Vector Labs Ab04622-10.3 Anti-SFTSV glycoprotein C [1H6-B10], Human IgG1, Fc Silent™, kappa (100 μg)

VECTOR LABS

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Quick Overview

The original antibody was generated by immunizing BLAB/c mice with SFTSV JS-2010-003 strain purified by β-propiolactone inactivation.

$570.70

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Description

Product Class: Purified
Clone ID: 1H6-B10
Heavy Chain Modification: Fc Silent™
Synonyms: SFTS; SFTSV; Glycoprotein C; SFTSV Gc; Envelopment polyprotein; Severe Fever and Thrombocytopenic Syndrome Virus; arthropod-borne phleboviruses
Amount: 100 μg
Application Codes Clone: ELISA
Shipping Temperature: Wet Ice
Buffer Composition: PBS with 0.02% Proclin 300.
Original Format: IgG1
Storage Temperature: Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C.
Chimeric Use Statement: This chimeric human antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.
Specificity Statement: This antibody binds the severe fever and thrombocytopenic syndrome virus glycoprotein C. Severe Fever with Thrombocytopenia Syndrome (SFTS) is an emerging infectious disease caused by the SFTS virus which is transmitted to humans through the bite of an infected tick. Most patients have symptoms such as fever, low platelet count and leukopenia, and may also have symptoms such as nausea, vomiting, diarrhea, headache, muscle pain, lymphatic enlargement, and bleeding. Recently, first case of human-to-human transmission of SFTS virus was reported in Japan.
Application Notes: The binding of this antibody towards SFTSV glycoprotein C was confirmed using ELISA. A double antibody sandwich ELISA was developed using 1H6-B10 as a coating antibody and HRP conjugated 1C5-F5 as a detection antibody. The detection system can detect from virus culture supernatant down to a sensitivity of about 60ng/ml (CN108178796).

Product Class:	Purified
Clone ID:	1H6-B10
Heavy Chain Modification:	Fc Silent™
Synonyms:	SFTS; SFTSV; Glycoprotein C; SFTSV Gc; Envelopment polyprotein; Severe Fever and Thrombocytopenic Syndrome Virus; arthropod-borne phleboviruses
Amount:	100 μg
Application Codes Clone:	ELISA
Shipping Temperature:	Wet Ice
Buffer Composition:	PBS with 0.02% Proclin 300.
Original Format:	IgG1
Storage Temperature:	Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C.
Chimeric Use Statement:	This chimeric human antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.
Specificity Statement:	This antibody binds the severe fever and thrombocytopenic syndrome virus glycoprotein C. Severe Fever with Thrombocytopenia Syndrome (SFTS) is an emerging infectious disease caused by the SFTS virus which is transmitted to humans through the bite of an infected tick. Most patients have symptoms such as fever, low platelet count and leukopenia, and may also have symptoms such as nausea, vomiting, diarrhea, headache, muscle pain, lymphatic enlargement, and bleeding. Recently, first case of human-to-human transmission of SFTS virus was reported in Japan.
Application Notes:	The binding of this antibody towards SFTSV glycoprotein C was confirmed using ELISA. A double antibody sandwich ELISA was developed using 1H6-B10 as a coating antibody and HRP conjugated 1C5-F5 as a detection antibody. The detection system can detect from virus culture supernatant down to a sensitivity of about 60ng/ml (CN108178796).

Specifications

More Information
Brand	Vector Labs
UNSPSC	12161500

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