Mfg Part Number
Ab04637-3.0
Vector Labs Ab04637-3.0 Anti-Thrombin [h1601-008], Mouse IgG2b, kappa (100 μg)
Quick Overview
The original antibody was raised by humanizing the heavy and light chain of antibody 1601.
$570.70
Order will ship within 1-3 business days
| Product Class: | Purified |
|---|---|
| Clone ID: | h1601-008 |
| Synonyms: | F2; Prothrombin; Coagulation factor II |
| Amount: | 100 μg |
| Application Codes Clone: | ELISA; SPR; in vivo; in vitro |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | IgG4 |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Chimeric Use Statement: | This chimeric mouse antibody was made using the variable domain sequences of the original Human IgG4 format, for improved compatibility with existing reagents, assays and techniques. |
| Specificity Statement: | This antibody is specific for human thrombin. |
| Application Notes: | The original antibody was used for an ELISA on human thrombin to determine the binding activity. This antibody was used for surface plasmon resonance on human thrombin. The antibody showed good affinity. The effect of this antibody on thrombinase activity was determined. It showed that it did not inhibit the enzymatic activity of thrombin on substrate S2228. This antibody was used for a human plasma APTT test, it showed increasing APTT values with increasing antibody concentrations. This antibody was tested in vivo. The antibodies were administered to cynomolgus monkeys, they significantly inhibited the formation of thrombosis (US20190315886A1). |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |