Mfg Part Number
Ab04674-10.29
Vector Labs Ab04674-10.29 Anti-SOD1 [591-37-M1], Human Fab fragment, His-Tagged, kappa (100 μg)
Quick Overview
The original antibody was raised by immunizing mice with Trx-bhSOD1-A4V.
$692.90
Order will ship within 1-3 business days
| Product Class: | Purified |
|---|---|
| Clone ID: | 591-37-M1 |
| Heavy Chain Modification: | His-Tagged |
| Synonyms: | SOD1; SOD1G93A; SOD1 A4V |
| Amount: | 100 μg |
| Application Codes Clone: | ELISA; IHC; FC; in vivo; IP |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | Fab |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Chimeric Use Statement: | This chimeric human antibody was made using the variable domain sequences of the original Mouse Fab format, for improved compatibility with existing reagents, assays and techniques. |
| Specificity Statement: | This antibody is specific for misfolded SOD1. |
| Application Notes: | This antibody was used for an ELISA on b-hSOD1, b-hSOD1-A4V, b-hSOD1-G85R and b-hSOD1-G93A. This antibody was used for immunoprecipitation on HEK-293T cells transfected with mutated human SOD1. The antibody was used for immunofluorescence on HEK-293T cells transiently transfected with hSOD1-G93A. The antibody was also used for immunohistochemistry on tissue from a mouse model of ALS, and on spinal cords of sporadic ALS patients, the mice expressed either hSOD1 or hSOD1-G93A. This antibody was used in vivo on mouse ALS models. It showed that the mice treated with the antibody maintained better weight and extended life (US9663586B2). |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |