Mfg Part Number
Ab04681-10.0
Vector Labs Ab04681-10.0 Anti-CD156b [hz1022C3], Human IgG1, kappa (100 μg)
Quick Overview
The original antibody was raised by immunzing a BALB/c mouse with human ADAM17 recombinant protein and then humanizing the resulting antibody.
$570.70
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| Product Class: | Purified |
|---|---|
| Clone ID: | hz1022C3 |
| Synonyms: | CSVP; TACE; ADAM17; ADAM 17; Snake venom-like protease; TNF-alpha convertase; TNF-alpha-converting enzyme; Disintegrin and metalloproteinase domain-containing protein 17 |
| Amount: | 100 μg |
| Application Codes Clone: | ELISA; FC; in vivo |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | IgG1 |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Specificity Statement: | This antibody is specific for the membrane proximal domain of ADAM17. |
| Application Notes: | The original antibody was used for an ELISA on human ADAM17 to determine its binding affinity. The antibody was used for flow cytometry on A172 human tumour cells to confirm that it could bind to cellular ADAM17. This antibody was used in vivo on mice in which A431 tumors were established, treatment with the antibody showed significant tumor inhibition and regression was observed in all animals, it achieved complete regression in two mice (US20180057601A1). |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |