Mfg Part Number
Ab04695-10.0
Vector Labs Ab04695-10.0 Anti-VEGF [2H1], Human IgG1, lambda (100 μg)
Quick Overview
The original antibody was raised by panning VEGF against a recombinant human antibody library containing 4.25 × 108 scFvs from non-immunized healthy donors^.
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| Product Class: | Purified |
|---|---|
| Clone ID: | 2H1 |
| Synonyms: | Vascular endothelial growth factor |
| Amount: | 100 μg |
| Application Codes Clone: | ELISA; in vitro; SPR |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | scFv |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Chimeric Use Statement: | This full-length, reformatted human antibody was made using the variable domain sequences of the original Human scFv format, for improved compatibility with existing reagents, assays and techniques. |
| Specificity Statement: | This amtibody is specific for the human VEGF protein. |
| Application Notes: | The original antibody was used for surface plasmon resonance on VEGF. This showed the binding affinity of the antibody to its antigen. This antibody was tested in vitro. It was assessed in a VEGF-stimulated HUVEC mitogenesis, it showed it was able to inhibit HUVEC proliferation in a dose dependent matter. This antibody was used for inhibition of VEGF-KDR binding. It showed that it was able to inhibit the binding. This antibody was used for an ELISA on different peptides of its antigen to determine its epitope (Lamdan et al., 2011; PMID:21167224, Lamdan et al., 2013; PMID:23702826). |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |